BDBM27947 2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl}phenyl)cyclohexyl]acetic acid::pyrimido[4,5-b][1,4]oxazine derivative, 2

SMILES: CC1(C(=Nc2c(ncnc2O1)N)c3ccc(cc3)C4CCC(CC4)CC(=O)O)C

InChI Key: InChIKey=FUIYMYNYUHVDPT-UHFFFAOYSA-N

Data: 13 IC50  1 EC50  1 Other

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 27947   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Human)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
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Diacylglycerol O-acyltransferase 2 (Human)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	22
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Diacylglycerol O-acyltransferase 1 (Rat)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	7.4	22
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Sterol O-acyltransferase 1 (Human)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Human)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Human)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Human)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Human)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Human)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Human)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Human)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Rat)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Human)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Human)	BDBM27947 (2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair