BDBM279762 US10035804, Example 33

SMILES CC1(C)N(C(=O)c2ccc(Cl)cc12)c1cncc(c1)N1CC2(CN(C2)C(=O)c2ncccn2)C1

InChI Key InChIKey=ZKMIAWAWWZXOCJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 279762   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM279762(US10035804, Example 33)
Affinity DataEC50:  1.75nMAssay Description:Herein we identified the use of the G-402 cell line as a host cell to ectopically express (transiently or stably) enzymes of the CYP11 family. Specif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM279762(US10035804, Example 33)
Affinity DataEC50:  0.0500nMAssay Description:Herein we identified the use of the G-402 cell line as a host cell to ectopically express (transiently or stably) enzymes of the CYP11 family. Specif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent