BDBM279855 US10028961, Compound 2::US10172864, Compound 2::US10946023, Compound 2

SMILES: C[C@@H](Nc1nc(N[C@H](C)C2CC2)nc(n1)-c1cccc(n1)C(F)(F)F)C1CC1

InChI Key: InChIKey=KRSKURCJOGAEOS-UHFFFAOYSA-N

Data: 13 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 279855   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isocitrate dehydrogenase [NADP] cytoplasmic [R132H] (Human)	BDBM279855 (US10028961, Compound 2 | US10172864, Compound 2 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
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Isocitrate dehydrogenase [NADP] cytoplasmic [R132C] (Human)	BDBM279855 (US10028961, Compound 2 | US10172864, Compound 2 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
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Isocitrate dehydrogenase [NADP], mitochondrial [R140Q] (Human)	BDBM279855 (US10028961, Compound 2 | US10172864, Compound 2 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic [R132H] (Human)	BDBM279855 (US10028961, Compound 2 | US10172864, Compound 2 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic [R132C] (Human)	BDBM279855 (US10028961, Compound 2 | US10172864, Compound 2 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP], mitochondrial [R140Q] (Human)	BDBM279855 (US10028961, Compound 2 | US10172864, Compound 2 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic [R132H] (Human)	BDBM279855 (US10028961, Compound 2 | US10172864, Compound 2 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic [R132C] (Human)	BDBM279855 (US10028961, Compound 2 | US10172864, Compound 2 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP], mitochondrial [R140Q] (Human)	BDBM279855 (US10028961, Compound 2 | US10172864, Compound 2 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Human)	BDBM279855 (US10028961, Compound 2 | US10172864, Compound 2 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP], mitochondrial (Human)	BDBM279855 (US10028961, Compound 2 | US10172864, Compound 2 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Human)	BDBM279855 (US10028961, Compound 2 | US10172864, Compound 2 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP], mitochondrial (Human)	BDBM279855 (US10028961, Compound 2 | US10172864, Compound 2 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair