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BDBM28016 6-[benzyl(ethyl)amino]-2-(2,6-dimethoxypyridin-3-yl)-N-(2-phenoxyethyl)pyridine-3-carboxamide::trisubstituted pyridine analogue, 18b

SMILES: CCN(Cc1ccccc1)c1ccc(C(=O)NCCOc2ccccc2)c(n1)-c1ccc(OC)nc1OC

InChI Key: InChIKey=DPISCHMOAFKKEG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28016   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium-sensing receptor (CaSR)


(Homo sapiens (Human))
BDBM28016
PNG
(6-[benzyl(ethyl)amino]-2-(2,6-dimethoxypyridin-3-y...)
Show SMILES CCN(Cc1ccccc1)c1ccc(C(=O)NCCOc2ccccc2)c(n1)-c1ccc(OC)nc1OC
Show InChI InChI=1S/C30H32N4O4/c1-4-34(21-22-11-7-5-8-12-22)26-17-15-24(29(35)31-19-20-38-23-13-9-6-10-14-23)28(32-26)25-16-18-27(36-2)33-30(25)37-3/h5-18H,4,19-21H2,1-3H3,(H,31,35)
PDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.05E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Company



Assay Description
Antagonist activity of test compounds was measured in HEK293 cells stably expressing the human recombinant CaR (HEK-CaR) by determining the ability o...


J Med Chem 52: 1204-8 (2009)


Article DOI: 10.1021/jm801178c
BindingDB Entry DOI: 10.7270/Q2416VCR
More data for this
Ligand-Target Pair