BDBM28017 6-{[(2S)-1-hydroxy-3-phenylpropan-2-yl]amino}-N-(2-phenoxyethyl)-2-(3,4,5-trimethoxyphenyl)pyridine-3-carboxamide::trisubstituted pyridine analogue, 18c

SMILES COc1cc(cc(OC)c1OC)-c1nc(N[C@H](CO)Cc2ccccc2)ccc1C(=O)NCCOc1ccccc1

InChI Key InChIKey=FCBOUJYKAGWYQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28017   

TargetExtracellular calcium-sensing receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM28017(6-{[(2S)-1-hydroxy-3-phenylpropan-2-yl]amino}-N-(2...)
Affinity DataIC50: 76nMAssay Description:Antagonist activity of test compounds was measured in HEK293 cells stably expressing the human recombinant CaR (HEK-CaR) by determining the ability o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed