BDBM281763 9-(2-acryloyl-1,2,3,4- tetrahydroisoquinolin- 5-yl)-8-fluoro-5H- pyrido[4,3-b]indole-6- carboxamide::US10023534, Example 31
SMILES NC(=O)c1cc(F)c(-c2cccc3CN(CCc23)C(=O)C=C)c2c3cnccc3[nH]c12
InChI Key InChIKey=YVNOLRLSCNMLIY-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 281763
Affinity DataIC50: 0.000300nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair