BDBM282858 (R)-6-(4-(3-chloro-4-fluorophenyl)-1-(3,3- difluorocyclopentyl)-1H-imidazol-5-yl)imidazo[1,2- b]pyridazine-3-carbonitrile::US10287295, Example 63'::US11352360, Example 63'::US9884868, Example 63'
SMILES Fc1ccc(cc1Cl)-c1ncn([C@@H]2CCC(F)(F)C2)c1-c1ccc2ncc(C#N)n2n1
InChI Key InChIKey=LUABADMUPNRBMU-CYBMUJFWSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 282858
Affinity DataIC50: 0.900nMpH: 7.4 T: 2°CAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 8.77E+3nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair