BDBM283 6-[(8-chloro-4-hydroxy-3-{[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzene]amido}-2-oxo-2H-chromen-7-yl)oxy]-5-hydroxy-3-methoxy-2,2-dimethyloxan-4-yl 5-methyl-1H-pyrrole-2-carboxylate::Clorobiocin::Coumarin-Based, DNA Gyrase Inhibitor::cid_54677920

SMILES COC1C(OC(=O)c2ccc(C)[nH]2)C(O)C(Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2Cl)OC1(C)C

InChI Key InChIKey=FJAQNRBDVKIIKK-UHFFFAOYSA-N

Data  3 IC50  1 ITC

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 283   

TargetProbable nicotinate-nucleotide adenylyltransferase(Staphylococcus aureus subsp. aureus N315)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

LigandBDBM283(6-[(8-chloro-4-hydroxy-3-{[4-hydroxy-3-(3-methylbu...)Copy SMILESCopy InChI

Affinity DataIC50:  7.01E+3nMMore data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

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In DepthDetails PCBioAssay
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TargetUDP-glucose 4-epimerase(Trypanosoma brucei)
University Of California San Diego

Curated by ChEMBL

LigandBDBM283(6-[(8-chloro-4-hydroxy-3-{[4-hydroxy-3-(3-methylbu...)Copy SMILESCopy InChI

Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of hexahistidine-tagged Trypanosoma brucei UDP-galactose-4'epimerase expressed in Escherichia coliMore data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar

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In DepthDetails ArticlePubMed
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TargetELAV-like protein 1 [I180A](Homo sapiens (Human))
University Of Texas Health Science Center

Curated by PubChem BioAssay

LigandBDBM283(6-[(8-chloro-4-hydroxy-3-{[4-hydroxy-3-(3-methylbu...)Copy SMILESCopy InChI

Affinity DataIC50:  4.19E+4nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBSimilars

In DepthDetails PCBioAssay
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