BDBM283026 6-(1-(2,2-difluoroethyl)-4-(2,4-difluorophenyl)-1H- imidazol-5-yl)imidazo[1,2-a]pyridine-3-carbonitrile::US9884868, Example 227'

SMILES FC(F)Cn1cnc(c1-c1ccc2ncc([N+]#[C-])n2c1)-c1ccc(F)cc1F

InChI Key InChIKey=YUOCFGASZCCEHD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 283026   

TargetTGF-beta receptor type-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM283026(6-(1-(2,2-difluoroethyl)-4-(2,4-difluorophenyl)-1H...)
Affinity DataIC50: >1.50E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM283026(6-(1-(2,2-difluoroethyl)-4-(2,4-difluorophenyl)-1H...)
Affinity DataIC50:  8.10nMpH: 7.4 T: 2°CAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent