BDBM28425 (2R,3R,4S,5R)-2-[6-amino-8-(methylamino)-9H-purin-9-yl]-5-({[4-(aminooxy)butyl](methyl)amino}methyl)oxolane-3,4-diol::AdoMet substrate analogue, 14a

SMILES CNc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CN(C)CCCCON)[C@@H](O)[C@H]1O

InChI Key InChIKey=OYHQCPMJWIRLBY-SDBHATRESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28425   

TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
Cornell University

LigandPNGBDBM28425((2R,3R,4S,5R)-2-[6-amino-8-(methylamino)-9H-purin-...)
Affinity DataIC50:  49nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed