BDBM284858 7-(1-((2,2-difluorocyclopropyl)methyl)-1H-indazol-6-yl)-5-(1- (tetrahydro-2H-pyran-4-yl)-1H-pyrazol-5-yl)pyrrolo[2,1-f][1,2,4] triazin-4-amine::US10023576, Example 48

SMILES Nc1ncnn2c(cc(-c3ccnn3C3CCOCC3)c12)-c1ccc2ncn(CC3CC3(F)F)c2c1

InChI Key InChIKey=GXHQQSQWWYMVDC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284858   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM284858(7-(1-((2,2-difluorocyclopropyl)methyl)-1H-indazol-...)
Affinity DataIC50:  3nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent