BDBM285003 3-(6-fluoro-2-methyl-1-oxoisoquinolin-4-yl) benzenesulfonamide::US10023592, Example 48::US10941160, Example 48

SMILES Cn1cc(-c2cccc(c2)S(N)(O)O)c2cc(F)ccc2c1=O

InChI Key InChIKey=VHZVKNSNYXGSFT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285003   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285003(3-(6-fluoro-2-methyl-1-oxoisoquinolin-4-yl) benzen...)
Affinity DataIC50:  2.75E+3nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285003(3-(6-fluoro-2-methyl-1-oxoisoquinolin-4-yl) benzen...)
Affinity DataIC50:  2.75E+3nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent