BDBM285062 3-amino-1-methyl-5-(3- methylsulfonylphenyl)pyridin-2-one::US10023592, Example 107

SMILES: Cn1cc(cc(N)c1=O)-c1cccc(c1)S(C)(=O)=O

InChI Key: InChIKey=YGUMCEDDFVYQNX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM285062 (3-amino-1-methyl-5-(3- methylsulfonylphenyl)pyridi...) Show SMILES Cn1cc(cc(N)c1=O)-c1cccc(c1)S(C)(=O)=O Show InChI InChI=1S/C13H14N2O3S/c1-15-8-10(7-12(14)13(15)16)9-4-3-5-11(6-9)19(2,17)18/h3-8H,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	7.3	n/a
Celgene Quanticel Research Inc US Patent					Assay Description Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...				US Patent US10023592 (2018) BindingDB Entry DOI: 10.7270/Q2668G7H
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