BDBM285062 3-amino-1-methyl-5-(3- methylsulfonylphenyl)pyridin-2-one::BDBM485906::US10023592, Example 107

SMILES Cn1cc(cc(N)c1=O)-c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=YGUMCEDDFVYQNX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285062   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285062(3-amino-1-methyl-5-(3- methylsulfonylphenyl)pyridi...)
Affinity DataIC50: >5.00E+3nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285062(3-amino-1-methyl-5-(3- methylsulfonylphenyl)pyridi...)
Affinity DataIC50: >5.00E+3nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent