BDBM285824 (6R,7R,8R)-8-(methoxymethyl)-4-azaspiro[2.5]octane-6,7-diol::US10081601, Example 6::US9796680, Example 6

SMILES COC[C@@H]1[C@@H](O)[C@H](O)CNC11CC1

InChI Key InChIKey=UREIBDHTHIOCAG-BWZBUEFSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285824   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Alectos Therapeutics

US Patent
LigandPNGBDBM285824((6R,7R,8R)-8-(methoxymethyl)-4-azaspiro[2.5]octane...)
Affinity DataIC50:  7.5nMAssay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Alectos Therapeutics

US Patent
LigandPNGBDBM285824((6R,7R,8R)-8-(methoxymethyl)-4-azaspiro[2.5]octane...)
Affinity DataIC50:  7.5nMpH: 7.0Assay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent