BDBM286 (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid::5-CHO-H4PteGlu1::Folinic Acid::LEUCOVORIN CALCIUM::LEVOLEUCOVORIN CALCIUM::Leucovorin::Levoleucovorin

SMILES: c1cc(ccc1C(=O)NC(CCC(=O)O)C(=O)O)NCC2CNC3=C(N2C=O)C(=O)NC(=N3)N

InChI Key: InChIKey=VVIAGPKUTFNRDU-UHFFFAOYSA-N

Data: 1 KI  1 ITC

PDB links: 24 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier organic anion transporter family member 1A3 (Rat)	BDBM286 ((2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,...) Show SMILES Show InChI	GoogleScholar	UniChem		8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 286

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
Serine Hydroxymethyltransferase (Rabbit)	BDBM286 ((2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,...)	GoogleScholar			-7.09	n/a	8.79	5.23	n/a	25
TBA					Details of this binding reaction