BindingDB BDBM286309 5-amino-1-cyclohexyl-3-(6- ethoxyquinolin-3-yl)-1H- pyrazole-4-carboxamide 1H NMR (500 MHz, MeOD) $#948; 8.85 (s, 1H), 8.31 (s, 1H), 7.99 (d, J = 9.2 Hz, 1H), 7.42 (d, J = 9.2 Hz, 1H), 7.13 (s, 1H), 4.15 (q, J = 6.9 Hz, 3H), 4.09 (s, 3H), 3.97- 3.79 (m, 1H), 1.93-1.83 (m, 6H), 1.48 (t, J= 6.9 Hz, 3H), 1.44-1.35 (m, 2H), 1.32-1.18 (m, 2H). MS (ESI) (M + H)+ = 380.5::US9518026, Example 102::US9956214, Compound 1655

BDBM286309 5-amino-1-cyclohexyl-3-(6- ethoxyquinolin-3-yl)-1H- pyrazole-4-carboxamide 1H NMR (500 MHz, MeOD) $#948; 8.85 (s, 1H), 8.31 (s, 1H), 7.99 (d, J = 9.2 Hz, 1H), 7.42 (d, J = 9.2 Hz, 1H), 7.13 (s, 1H), 4.15 (q, J = 6.9 Hz, 3H), 4.09 (s, 3H), 3.97- 3.79 (m, 1H), 1.93-1.83 (m, 6H), 1.48 (t, J= 6.9 Hz, 3H), 1.44-1.35 (m, 2H), 1.32-1.18 (m, 2H). MS (ESI) (M + H)+ = 380.5::US9518026, Example 102::US9956214, Compound 1655

SMILES CCOc1ccc2ncc(cc2c1)-c1nn(C2CCCCC2)c(N)c1C(N)=O

InChI Key InChIKey=IJFPWYFPGXYILN-UHFFFAOYSA-N

Data 4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 286309

Calmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For Commercialization

US Patent

BDBM286309(5-amino-1-cyclohexyl-3-(6- ethoxyquinolin-3-yl)-1H...)

IC50: >2.00E+3nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
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PC cid PC sid

Details US Patent

Calcium-dependent protein kinase 1(Cryptosporidium parvum)
University Of Washington Through Its Center For Commercialization

US Patent