BindingDB PrimarySearch

BDBM28681 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione::Avandia::BRL 49653::Brl-49653::CHEMBL121::ROSIGLITAZONE MALEATE::[3H]rosiglitazone::cid_5281055::rosiglitazone

SMILES: CN(CCOc1ccc(Cc2sc(=O)[nH]c2O)cc1)c1ccccn1

InChI Key: InChIKey=FLDPBMANMDLQTH-UHFFFAOYSA-N

Data: 21 KI 59 IC50 4 Kd 140 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 222 hits for monomerid = 28681
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
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Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	14.8	3.80	n/a	n/a	7.5	37
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	82	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	>1.20E+4	n/a	n/a	7.2	15
TBA								Citation and Details
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Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	274	n/a	223	n/a	n/a	7.4	23
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Protein LANA1 (HHV-8)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a
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Corticotropin-releasing factor-binding protein (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	>5.30E+4	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Mouse)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Mouse)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	657	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	2.88E+3	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.62E+3	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM28681 (cid_5281055 \| [3H]rosiglitazone \| CHEMBL121 \| ROSI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
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