BDBM28752 2-[4-({[3-(4-chlorophenyl)-1,2,4-thiadiazol-5-yl]methyl}sulfanyl)-2-methylphenoxy]-2-methylpropanoic acid::[1,2,4]thiadiazole derivative, 30

SMILES Cc1cc(SCc2nc(ns2)-c2ccc(Cl)cc2)ccc1OC(C)(C)C(O)=O

InChI Key InChIKey=CHWARMCOUPSGEK-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 28752   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM28752(2-[4-({[3-(4-chlorophenyl)-1,2,4-thiadiazol-5-yl]m...)
Affinity DataEC50:  186nMAssay Description:The HEK293 cells were co-transfected with DNA constructs containing the ligand-binding domain of PPAR and Gal4-luciferase reporter. The luciferase ac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM28752(2-[4-({[3-(4-chlorophenyl)-1,2,4-thiadiazol-5-yl]m...)
Affinity DataEC50: >3.00E+3nMAssay Description:The HEK293 cells were co-transfected with DNA constructs containing the ligand-binding domain of PPAR and Gal4-luciferase reporter. The luciferase ac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM28752(2-[4-({[3-(4-chlorophenyl)-1,2,4-thiadiazol-5-yl]m...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human PPARdelta-Gal4 in HEK293 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM28752(2-[4-({[3-(4-chlorophenyl)-1,2,4-thiadiazol-5-yl]m...)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human PPARgamma-Gal4 in HEK293 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM28752(2-[4-({[3-(4-chlorophenyl)-1,2,4-thiadiazol-5-yl]m...)
Affinity DataEC50:  186nMAssay Description:Agonist activity at human PPARalpha-Gal4 in HEK293 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM28752(2-[4-({[3-(4-chlorophenyl)-1,2,4-thiadiazol-5-yl]m...)
Affinity DataEC50:  18nMAssay Description:The confluent HEK293 cells were co-transfected with DNA construct containing PPARdelta-Gal4 chimeric receptor and Gal4-luciferase reporter. The lucif...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed