BDBM288068 N-(3-chloro-2-fluorobenzyl)- trans-3-ethoxy-9'-hydroxy- 2'-methyl-1',8'-dioxo- 1',2',3',8'- tetrahydrospiro[cyclobutane- 1,4'-pyrido[1,2-a]pyrazine]- 7'-carboxamide hydrochloride::US10087178, Example S28

SMILES CCO[C@H]1C[C@]2(C1)CN(C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1cccc(Cl)c1F

InChI Key InChIKey=OJEGUEGSWHALRO-MRAWUWRDSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288068   

TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288068(N-(3-chloro-2-fluorobenzyl)- trans-3-ethoxy-9'-hyd...)
Affinity DataEC50:  3.60nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent