BDBM288092 N-(2,4-difluorobenzyl)-9'- hydroxy-2'-isopropyl-trans- 3-methoxy-1',8'-dioxo- 1',2',4',8'- tetrahydrospiro[cyclobutane- 1,3'-pyrido[1,2-a]pyrazine]- 7'-carboxamide hydrochloride::US10087178, Example S52

SMILES CO[C@H]1C[C@]2(C1)Cn1cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c1C(=O)N2C(C)C

InChI Key InChIKey=NVINTTDVKJFBLH-CWSKOGRWSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288092   

TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288092(N-(2,4-difluorobenzyl)-9'- hydroxy-2'-isopropyl-tr...)
Affinity DataEC50:  3.5nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent