BDBM288121 Production of (E)-4-[7′-(3-chloro-2-fluorobenzylcarbamoyl)-cis-3-(methoxymethyl)-2′-methyl-1′,8′-dioxo-1′,2′,3′,8′-tetrahydrospiro[cyclobutane-1,4′-pyrido[1,2-a]pyrazin]-9′-yloxy]-4-oxobut-2-enoic acid::US10087178, Example 39

SMILES COC[C@H]1C[C@@]2(C1)CN(C)C(=O)c1c(OC(=O)\C=C\C(O)=O)c(=O)c(cn21)C(=O)NCc1cccc(Cl)c1F

InChI Key InChIKey=GTQKSWMAJVOYPO-PJCPLUNWSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288121   

TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288121(Production of (E)-4-[7′-(3-chloro-2-fluorobe...)
Affinity DataEC50:  1.40nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent