BDBM28817 5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine::DSM74::triazolopyrimidine-based compound, DSM74

SMILES: Cc1cc(n2c(n1)ncn2)Nc3ccc(cc3)C(F)(F)F

InChI Key: InChIKey=LRHHXKBKRNNFRV-UHFFFAOYSA-N

Data: 8 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 28817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum (isolate 3D7))	BDBM28817 (5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	8.0	20
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Dihydroorotate dehydrogenase (quinone), mitochondrial [100-517] (Plasmodium berghei (strain Anka))	BDBM28817 (5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Human)	BDBM28817 (5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum (isolate 3D7))	BDBM28817 (5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM28817 (5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM28817 (5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (quinone), mitochondrial (Rat)	BDBM28817 (5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (quinone), mitochondrial (Mouse)	BDBM28817 (5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair