BDBM288173 (1S,2S)-N-(2,4- difluorobenzyl)-9'-hydroxy- 2'-isopropyl-2- (methoxymethyl)-1',8'-dioxo- 1',2',4',8'- tetrahydrospiro[cyclopropane- 1,3'-pyrido[1,2-a]pyrazine]- 7'-carboxamide::US10087178, Example T41

SMILES COC[C@H]1C[C@@]11Cn2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C(=O)N1C(C)C

InChI Key InChIKey=DDUZRLFLPDAWJH-QKFKETGDSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288173   

TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288173((1S,2S)-N-(2,4- difluorobenzyl)-9'-hydroxy- 2'-iso...)
Affinity DataEC50:  2.20nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent