BDBM288306 7-Chloro-5-[6-(difluoromethyl)-4-methyl-2-::US10087185, Example 124

SMILES Cc1cc(C(F)F)c(-c2cc3CC(=O)Nc3c(Cl)c2)n2nc(cc12)C(F)(F)F

InChI Key InChIKey=DHDWJBZKHOPHLK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288306   

TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288306(7-Chloro-5-[6-(difluoromethyl)-4-methyl-2- | US100...)
Affinity DataIC50:  0.251nMpH: 7.4Assay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent