BDBM289824 US10093683, Example 129A::US10093683, Example 129B
SMILES COC(=O)Nc1ccc(cc1)-c1nnc(o1)C(Cc1ccccc1)C(=O)N1CC[C@@]2(C1)OC(=O)Nc1ccc(Cl)c(F)c21
InChI Key InChIKey=KAMJPVPVOULBJY-QOWRFBDLSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 289824
Affinity DataKi: 320nM ΔG°: -8.85kcal/molepH: 7.4 T: 2°CAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Affinity DataKi: >875nM ΔG°: >-8.26kcal/molepH: 7.4 T: 2°CAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair