BDBM289850 N((S)-1-((R)-6-chloro-5-fluoro-2-oxo-1,2-dihydrospiro[benzo[d][1,3]oxazine-4,3′-piperidin]-1′-yl)-1-oxo-3-phenylpropan-2-yl)-3-(trifluoromethyl)-1H-indazole-5-carboxamide::US10093683, Example 256
SMILES Fc1c(Cl)ccc2NC(=O)O[C@]3(CCCN(C3)C(=O)[C@H](Cc3ccccc3)NC(=O)c3ccc4[nH]nc(c4c3)C(F)(F)F)c12
InChI Key
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 289850
Affinity DataKi: >875nM ΔG°: >-8.26kcal/molepH: 7.4 T: 2°CAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair