BDBM289868 3-Methyl-1-{6-[5-(2H-pyrazol-3- yl)-pyridin-2-yloxy]-naphthalen-2- ylmethyl}-azetidin-3-ol::US9573957, Example 11

SMILES CC1(O)CN(Cc2ccc3cc(Oc4ccc(cn4)-c4ccn[nH]4)ccc3c2)C1

InChI Key InChIKey=HQEADKQGOVSNBY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289868   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289868(3-Methyl-1-{6-[5-(2H-pyrazol-3- yl)-pyridin-2-ylox...)
Affinity DataIC50:  0.530nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent