BDBM29025 cyanohydroxybutenamide, 10

SMILES CC(=O)C(C#N)C(=O)Nc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=KECIZMPXZLKEHL-UHFFFAOYSA-N

Data  2 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29025   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Leeds

LigandPNGBDBM29025(cyanohydroxybutenamide, 10)
Affinity DataKi:  11nM IC50:  90nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Leeds

LigandPNGBDBM29025(cyanohydroxybutenamide, 10)
Affinity DataKi:  3.00E+3nM ΔG°:  -7.53kcal/mole IC50:  2.57E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed