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BDBM290461 3-[4-(4-Cyanonaphthalen-1-yl)-1-benzothiophen-2-yl]-2,2-dimethyl propionic Acid ::US10100016, Compound 38

SMILES: CC(C)(Cc1cc2c(cccc2s1)-c1ccc(C#N)c2ccccc12)C(O)=O

InChI Key: InChIKey=QBPYGFBXFNXDNK-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 290461   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290461
PNG
(3-[4-(4-Cyanonaphthalen-1-yl)-1-benzothiophen-2-yl...)
Show SMILES CC(C)(Cc1cc2c(cccc2s1)-c1ccc(C#N)c2ccccc12)C(O)=O
Show InChI InChI=1S/C24H19NO2S/c1-24(2,23(26)27)13-16-12-21-19(8-5-9-22(21)28-16)20-11-10-15(14-25)17-6-3-4-7-18(17)20/h3-12H,13H2,1-2H3,(H,26,27)
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PC cid
PC sid
UniChem
US Patent
n/an/a 209n/an/an/an/an/an/a



Shanghai Yingli Pharmaceutical Co., Ltd

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)


BindingDB Entry DOI: 10.7270/Q2TH8PQZ
More data for this
Ligand-Target Pair