BindingDB logo
myBDB logout

BDBM290502 US10099993, Compound 83

SMILES: CC(C)CC(=O)c1ccc(OCCCCOc2ccc(cc2)C#N)c(C)c1O

InChI Key: InChIKey=DBKPJNPEJIYDMX-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 290502   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 3


(Homo sapiens (Human))
BDBM290502
PNG
(US10099993, Compound 83)
Show SMILES CC(C)CC(=O)c1ccc(OCCCCOc2ccc(cc2)C#N)c(C)c1O
Show InChI InChI=1S/C23H27NO4/c1-16(2)14-21(25)20-10-11-22(17(3)23(20)26)28-13-5-4-12-27-19-8-6-18(15-24)7-9-19/h6-11,16,26H,4-5,12-14H2,1-3H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>3.00E+4n/an/an/an/a



Sanford-Burnham Medical Research Institute

US Patent




US Patent US10099993 (2018)


BindingDB Entry DOI: 10.7270/Q2Z89FFP
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM290502
PNG
(US10099993, Compound 83)
Show SMILES CC(C)CC(=O)c1ccc(OCCCCOc2ccc(cc2)C#N)c(C)c1O
Show InChI InChI=1S/C23H27NO4/c1-16(2)14-21(25)20-10-11-22(17(3)23(20)26)28-13-5-4-12-27-19-8-6-18(15-24)7-9-19/h6-11,16,26H,4-5,12-14H2,1-3H3
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>3.00E+4n/an/a7.325



Sanford-Burnham Medical Research Institute

US Patent


Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


US Patent US10099993 (2018)


BindingDB Entry DOI: 10.7270/Q2Z89FFP
More data for this
Ligand-Target Pair