BDBM292049 3-(7-Chloro-1H-indazol-5-yl)-2-ethyl-5-(trifluoromethyl)-2H-pyrazolo[4,3-::US10100045, Example 20

SMILES CCn1nc2ccc(nc2c1-c1cc(Cl)c2[nH]ncc2c1)C(F)(F)F

InChI Key InChIKey=NAWGKZPAOIEYEZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292049   

TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292049(3-(7-Chloro-1H-indazol-5-yl)-2-ethyl-5-(trifluorom...)
Affinity DataIC50:  0.398nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent