BDBM292050 5-(2-Isopropyl-5-(trifluoromethyl)-2H-pyrazolo[4,3-b]pyridin-3-yl)-7-methylindolin-::US10100045, Example 21

SMILES CC(C)n1nc2ccc(nc2c1-c1cc2CC(=O)Nc2c(C)c1)C(F)(F)F

InChI Key InChIKey=MRMQJBAGEHRZAD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292050   

TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292050(5-(2-Isopropyl-5-(trifluoromethyl)-2H-pyrazolo[4,3...)
Affinity DataIC50:  0.398nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent