BDBM2937 4-(2-cyclopropylethynyl)-6-methyl-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one::Efavirenz deriv. 4p

SMILES Cc1ccc2NC(=O)OC(C#CC3CC3)(c2c1)C(F)(F)F

InChI Key InChIKey=MTBMZSCUASYCQH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2937   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM2937(4-(2-cyclopropylethynyl)-6-methyl-4-(trifluorometh...)
Affinity DataIC50:  133nMpH: 8.2 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed