BDBM29400 CHEMBL374184::tacrine-dihydropyridine hybrid (tacripyrine), 11
SMILES CCOC(=O)C1C(c2ccc(OC)cc2)c2c(N)c3CCCCc3nc2N=C1C
InChI Key InChIKey=ALABVFKYOIAJBJ-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 29400
Affinity DataIC50: 105nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of Electrophorus electricus AChEMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human serum BuChEMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of Electrophorus electricus AChE by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of human erythrocyte AChEMore data for this Ligand-Target Pair