BDBM294364 US9586959, Compound 12

SMILES CN1CCN(CC1)c1nc2ncc(Br)cc2n2cnnc12

InChI Key InChIKey=AAGGRTPMBWISNV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 294364   

TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294364(US9586959, Compound 12)
Affinity DataIC50:  67nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294364(US9586959, Compound 12)
Affinity DataIC50:  7.10E+4nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes measured after 30 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294364(US9586959, Compound 12)
Affinity DataIC50:  67nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed