BDBM294506 N,3-Dimethyl-6-{2-[4-(2-oxopyrrolidin-1-yl)-1-phenyl-1H-imidazol-2-yl]ethyl}-2-(trifluoromethyl)imidazo[1,2-b]pyridazine-8-carb oxamide::US9586970, 27
SMILES CNC(=O)c1cc(CCc2nc(cn2-c2ccccc2)N2CCCC2=O)nn2c(C)c(nc12)C(F)(F)F
InChI Key InChIKey=CKYUWBFWPFMZHC-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 294506
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 2.90nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair