BDBM29529 ML10302 scaffold, 14
SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCC(CC1)NC(=O)CCCNCCCc1ccc(CCCNCCCC(=O)NC2CCN(CCOC(=O)c3cc(Cl)c(N)cc3OC)CC2)cc1
InChI Key InChIKey=AVRFLKAGKYQYFW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 29529
Affinity DataKi: 14nM ΔG°: -10.7kcal/mole EC50: 9nMpH: 7.4 T: 2°CAssay Description:Radioligand binding studies were performed in buffer contains test compound, [3H]-GR113808, and receptor C6 glial cell membrane preparation. Nonspeci...More data for this Ligand-Target Pair
Affinity DataEC50: 9.00E+3nMAssay Description:EC/IC50 was the effective concentration of agonist inhibiting the formation of A-beta fibrils to 50% of the control value. Three independent measurem...More data for this Ligand-Target Pair