BDBM29529 ML10302 scaffold, 14

SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCC(CC1)NC(=O)CCCNCCCc1ccc(CCCNCCCC(=O)NC2CCN(CCOC(=O)c3cc(Cl)c(N)cc3OC)CC2)cc1

InChI Key InChIKey=AVRFLKAGKYQYFW-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29529   

Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Cnrs

LigandPNGBDBM29529(ML10302 scaffold, 14)
Affinity DataKi:  14nM ΔG°:  -10.7kcal/mole EC50:  9nMpH: 7.4 T: 2°CAssay Description:Radioligand binding studies were performed in buffer contains test compound, [3H]-GR113808, and receptor C6 glial cell membrane preparation. Nonspeci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Cnrs

LigandPNGBDBM29529(ML10302 scaffold, 14)
Affinity DataEC50:  9.00E+3nMAssay Description:EC/IC50 was the effective concentration of agonist inhibiting the formation of A-beta fibrils to 50% of the control value. Three independent measurem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed