BDBM29571 isatin sulfonamide, 10a

SMILES O=C1N(Cc2ccccc2)c2ccc(cc2C1=O)S(=O)(=O)N1CCSCC1

InChI Key InChIKey=VIDUBXGYLLMUAS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 29571   

TargetCaspase-1(Homo sapiens (Human))
Washington University

LigandPNGBDBM29571(isatin sulfonamide, 10a)
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Washington University

LigandPNGBDBM29571(isatin sulfonamide, 10a)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM29571(isatin sulfonamide, 10a)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Washington University

LigandPNGBDBM29571(isatin sulfonamide, 10a)
Affinity DataIC50:  1.28E+4nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

LigandPNGBDBM29571(isatin sulfonamide, 10a)
Affinity DataIC50:  1.48E+3nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM29571(isatin sulfonamide, 10a)
Affinity DataIC50:  1.03E+3nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed