BDBM297586 US10118902, Example 88::US10584103, Example 88::{2-cyclopropyl-4-[4-(2-methoxy- phenyl)-piperidin-1-yl]-quinazolin- 6-ylmethyl}-methyl-(2-morpholin- 4-yl-ethyl)-amine

SMILES COc1ccccc1C1CCN(CC1)c1nc(nc2ccc(CN(C)CCN3CCOCC3)cc12)C1CC1

InChI Key InChIKey=KRLIYOISKXMOOS-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297586   

TargetNeurotensin receptor type 1(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297586(US10118902, Example 88 | US10584103, Example 88 | ...)
Affinity DataEC50: >1.00E+4nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 μL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297586(US10118902, Example 88 | US10584103, Example 88 | ...)
Affinity DataEC50: >1.00E+4nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 uL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 at a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent