BDBM29923 US11066414, Comparative Example 1::substituted 6-aminoquinoline-3-carbonitrile, 34

SMILES: CCN1CCC(CC1)n1cc(CNc2cc(Cl)c3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)nn1

InChI Key: InChIKey=PHNZIIMWDVXPGG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 8 (Human)	BDBM29923 (substituted 6-aminoquinoline-3-carbonitrile, 34 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM29923 (substituted 6-aminoquinoline-3-carbonitrile, 34 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	357	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair