BDBM299256 6-(2-fluoro-4-pyridyl)pyrido[3,2-d]pyrimidin-4-amine::US9592235, Example 1::US9855269, Compound 154

SMILES: Nc1ncnc2ccc(nc12)-c1ccnc(F)c1

InChI Key: InChIKey=CLODUYRNZMIONW-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 299256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase kinase 4 (Human)	BDBM299256 (US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11.5	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase kinase 4 (Human)	BDBM299256 (US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11.5	n/a	n/a	n/a	n/a	n/a	n/a
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Misshapen-like kinase 1 (Human)	BDBM299256 (US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	199	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase kinase 4 (Human)	BDBM299256 (US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
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TRAF2 and NCK-interacting protein kinase (Human)	BDBM299256 (US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
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TRAF2 and NCK-interacting protein kinase (Human)	BDBM299256 (US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Human)	BDBM299256 (US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Misshapen-like kinase 1 (Human)	BDBM299256 (US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair