BDBM299365 6-(3-chloro-5- fluoro-phenyl) quinazolin-4- amine::US9592235, Example 171::US9855269, Compound 15
SMILES Nc1ncnc2ccc(cc12)-c1cc(F)cc(Cl)c1
InChI Key InChIKey=QWGJBVJDHIRFFJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 299365
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 226nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 226nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair