BDBM299365 6-(3-chloro-5- fluoro-phenyl) quinazolin-4- amine::US9592235, Example 171::US9855269, Compound 15

SMILES Nc1ncnc2ccc(cc12)-c1cc(F)cc(Cl)c1

InChI Key InChIKey=QWGJBVJDHIRFFJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299365   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM299365(6-(3-chloro-5- fluoro-phenyl) quinazolin-4- amine ...)
Affinity DataIC50:  226nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM299365(6-(3-chloro-5- fluoro-phenyl) quinazolin-4- amine ...)
Affinity DataIC50:  226nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent