BindingDB logo
myBDB logout

BDBM29945 piperidine-1-carboxamide, 21h

SMILES: [H][C@]1(CCCN(C1)C(=O)N[C@H](CNC)CC1CCCCC1)[C@@](O)(CCCCOC)c1cccc(C)c1

InChI Key: InChIKey=KLQZJOZYDBPUFR-SJIBRTEWNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29945   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Renin


(Homo sapiens (Human))
BDBM29945
PNG
(piperidine-1-carboxamide, 21h)
Show SMILES CNC[C@H](CC1CCCCC1)NC(=O)N1CCC[C@H](C1)[C@@](O)(CCCCOC)c1cccc(C)c1
Show InChI InChI=1/C29H49N3O3/c1-23-11-9-14-25(19-23)29(34,16-7-8-18-35-3)26-15-10-17-32(22-26)28(33)31-27(21-30-2)20-24-12-5-4-6-13-24/h9,11,14,19,24,26-27,30,34H,4-8,10,12-13,15-18,20-22H2,1-3H3,(H,31,33)/t26-,27+,29-/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.5n/an/an/an/a7.022



Vitae Pharmaceuticals



Assay Description
The activity of renin inhibitors in vitro was measured using the FRET assay, which was carried out in flat-bottom white opaque microtiter plates. The...


Bioorg Med Chem Lett 19: 3541-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.140
BindingDB Entry DOI: 10.7270/Q2D21VXV
More data for this
Ligand-Target Pair