BDBM29957 piperidine-1-carboxamide, 21t
SMILES [H][C@]1(CCCN(C1)C(=O)N[C@H](CNC)CC1CCCCC1)[C@@](O)(CCCCOC)c1cccc(Cl)c1F
InChI Key InChIKey=LBPSWVGVKWEHLP-IWHLBADBSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 29957
Affinity DataIC50: 0.100nMT: 2°CAssay Description:The activity of renin inhibitors in vitro was measured using the FRET assay, which was carried out in flat-bottom white opaque microtiter plates. The...More data for this Ligand-Target Pair
Affinity DataIC50: 0.730nMAssay Description:Inhibition of human recombinant renin using DABCYL-gamma-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS as substrate for 60 mins by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibition of renin in human plasma assessed as formation of angiotensin1 product after 90 mins by competitive radioimmunoassayMore data for this Ligand-Target Pair