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BDBM29975 arylpyrazole, 20

SMILES: CCc1ccc(cn1)-c1c(C)c(CNC2CCCC2)nn1-c1ncccc1Cl

InChI Key: InChIKey=PZQFSAKJIPMDST-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29975   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))
BDBM29975
PNG
(arylpyrazole, 20)
Show SMILES CCc1ccc(cn1)-c1c(C)c(CNC2CCCC2)nn1-c1ncccc1Cl
Show InChI InChI=1S/C22H26ClN5/c1-3-17-11-10-16(13-25-17)21-15(2)20(14-26-18-7-4-5-8-18)27-28(21)22-19(23)9-6-12-24-22/h6,9-13,18,26H,3-5,7-8,14H2,1-2H3
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Similars

Article
PubMed
n/an/a 67n/an/an/an/a7.437



Banyu Pharmaceutical Co.



Assay Description
Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...


Bioorg Med Chem Lett 19: 3627-31 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.116
BindingDB Entry DOI: 10.7270/Q289145G
More data for this
Ligand-Target Pair