BDBM299819 4-(4-{[(4- aminopyrimidin-5- yl)oxy]methyl} piperidin-1- yl)-6-[(1- cyanocyclopropyl) methoxy]-N-(2,2- dimethylpropyl)- 1,3,5-triazine-2- carboxamide::US9593097, Example 189

SMILES CC(C)(C)CNC(=O)c1nc(OCC2(CC2)C#N)nc(n1)N1CCC(COc2cncnc2N)CC1

InChI Key InChIKey=AVELQMUUDDGPIP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299819   

TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM299819(4-(4-{[(4- aminopyrimidin-5- yl)oxy]methyl} piperi...)
Affinity DataKi:  4.83nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent