BDBM300458 6-(3-fluorophenyl)-N-{3-[(morpholin-4-ylacetyl)amino]-4-(trifluoromethoxy)phenyl}nicotinamide::US10130633, Example 28
SMILES Fc1cccc(c1)-c1ccc(cn1)C(=O)Nc1ccc(OC(F)(F)F)c(NC(=O)CN2CCOCC2)c1
InChI Key InChIKey=FIXTUTUYLQVSOC-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 300458
Affinity DataIC50: 52.3nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:HEK293 cells were cotransfected with the FOP control vector and pcDNA3. The FOP vector is identical to the TOP construct, but it contains instead of ...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair