BDBM300479 3-({[1-(4-methylpiperazin-1-yl)cyclopropyl]carbonyl}amino)-4-[(methylsulfonyl)methyl]-N-(5-phenyl-1,3,4-thiadiazol-2-yl)benzamide::US10130633, Example 49
SMILES CN1CCN(CC1)C1(CC1)C(=O)Nc1cc(ccc1CS(C)(=O)=O)C(=O)Nc1nnc(s1)-c1ccccc1
InChI Key InChIKey=DYFZAXBGBVBDTJ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 300479
Affinity DataIC50: 46.6nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:HEK293 cells were cotransfected with the FOP control vector and pcDNA3. The FOP vector is identical to the TOP construct, but it contains instead of ...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair