BDBM300498 N-[6-(2-fluorophenyl)pyridin-3-yl]-3-({[1-(morpholin-4-yl)cyclopropyl]carbonyl}amino)-4-(trifluoromethoxy)benzamide::US10130633, Example 68

SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)C3(CC3)N3CCOCC3)c2)cn1

InChI Key InChIKey=CWKJBWOIRXMPCC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 300498   

TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300498(N-[6-(2-fluorophenyl)pyridin-3-yl]-3-({[1-(morphol...)
Affinity DataIC50:  7.72nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300498(N-[6-(2-fluorophenyl)pyridin-3-yl]-3-({[1-(morphol...)
Affinity DataIC50: >5.00E+4nMAssay Description:HEK293 cells were cotransfected with the FOP control vector and pcDNA3. The FOP vector is identical to the TOP construct, but it contains instead of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300498(N-[6-(2-fluorophenyl)pyridin-3-yl]-3-({[1-(morphol...)
Affinity DataIC50:  5.17nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300498(N-[6-(2-fluorophenyl)pyridin-3-yl]-3-({[1-(morphol...)
Affinity DataIC50: >5.00E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent